Molecular Genetic Contributions to Social Deprivation and Household Income in UK Biobank
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- 作者：W. David Hill1 ; 2 ; 10 ; david.hill@ed.ac.uk" class="auth_mail" title="E-mail the corresponding author ; Saskia P. Hagenaars1 ; 2 ; 3 ; 10 ; Riccardo E. Marioni1 ; 4 ; 5 ; Sarah E. Harris1 ; 4 ; David C.M. Liewald1 ; 2 ; Gail Davies1 ; 2 ; Aysu Okbay6 ; 7 ; 8 ; Andrew M. McIntosh3 ; Catharine R. Gale1 ; 2 ; 9 ; Ian J. Deary1 ; 2 ; 11 ; ian.deary@ed.ac.uk" class="auth_mail" title="E-mail the corresponding author
- 关键词：GWAS ; genetics ; genetic correlation ; UK Biobank ; socioeconomic status ; SES ; income ; social deprivation
- 刊名：Current Biology
- 出版年：2016
- 出版时间：21 November 2016
- 年：2016
- 卷：26
- 期：22
- 页码：3083-3089
- 全文大小：2481 K
文摘
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Common SNPs explain 21% of social deprivation and 11% of household income
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Two loci attained genome-wide significance for household income
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Genes in these loci have been linked to synaptic plasticity
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Genetic correlations were found between both measures of SES and many other traits