Fibroblast growth factor 5-short (FGF5s) inhibits the activity of FGF5 in primary and secondary hair follicle dermal papilla cells of cashmere goats
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- 作者：Xiaolin Hea ; hesibonnie0@163.com" class="auth_mail" title="E-mail the corresponding author ; Yuan Chaoa ; b ; yuch_0294215@126.com" class="auth_mail" title="E-mail the corresponding author ; Guangxian Zhoua ; royouzhouguang@126.com" class="auth_mail" title="E-mail the corresponding author ; Yulin Chena ; chenyulin@nwafu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：FGF5 ; fibroblast growth factor 5 ; FGF5s ; fibroblast growth factor 5-short ; PHF ; primary hair follicle ; SHF ; secondary hair follicle ; FGFR1 ; fibroblast growth factor receptor 1 ; IGF-1 ; insulin-like growth factor-1 ; BMP4 ; bone morphogenetic protein 4 ; DMEM/F12 ; Dulbecco's Modified Eagle Media ; Nutrient Mixture F-12 ; FBS ; fetal bovine serum ; PBS ; phosphate buffer saline ; α-SMA ; smooth muscle α-actin ; IgG ; immunoglobulin G ; DAPI ; 4&prime ; 6&prime ; -diamidino-2-phenylindole ; GFP ; green fluorescent pro
- 刊名：Gene
- 出版年：2016
- 出版时间：10 January 2016
- 年：2016
- 卷：575
- 期：2
- 页码：393-398
- 全文大小：1173 K
文摘
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FGFR1 was expressed in dermal papilla cells of cashmere goats.
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FGF5 overexpression increased the mRNA expression of IGF-1, versican and noggin.
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FGF5 overexpression decreased the mRNA expression of BMP4.
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FGF5s overexpression partly inhibited FGF5's effects in dermal papilla cells.