Impaired function of α2-containing nicotinic acetylcholine receptors on oriens-lacunosum moleculare cells causes hippocampus-dependent memory impairments
α2KO mice have impaired hippocampus-dependent memory. Maternal-nicotine-exposed α2KO mice do not show increased CA1 network excitation. Maternal-nicotine-treated α2KO mice do not have facilitated induction of LTP.