A facile label-free G-quadruplex based fluorescent aptasensor method for rapid detection of ATP

详细信息    查看全文

• 作者：Haisheng Liu^a ; Changbei Ma^a ; ^{macb2012@csu.edu.cn} ; Feng Ning^a ; Hanchun Chen^a ; Hailun He^a ; Kemin Wang^b ; Jun Wang^a
• 关键词：ATP ; Label-free ; Aptasensor ; Thioflavin T ; G-quadruplex formation
• 刊名：Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
• 出版年：2017
• 出版时间：15 March 2017
• 年：2017
• 卷：175
• 期：Complete
• 页码：164-167
• 全文大小：497 K
• 卷排序：175

文摘

A novel fluorescence method based on G-quadruplex formation was developed for detection of ATP. Thioflavin T was used as a fluorescent indicator. A low detection limit (18 nM) was obtained without any amplification. The method is simple, sensitive, rapid and cost-effective.