UVB irradiation-enhanced zinc oxide nanoparticles-induced DNA damage and cell death in mouse skin
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- 作者：Anu Pala ; e ; Shamshad Alama ; Sandeep Mittald ; f ; Nidhi Arjariab ; Jai Shankarb ; Mahadeo Kumarc ; Dhirendra Singhc ; Alok Kumar Pandeyd ; e ; Kausar Mahmood Ansaria ; kmansari@iitr.res.in" class="auth_mail" title="E-mail the corresponding author
- 关键词：Zinc oxide nanoparticles ; DNA damage ; SKH-1 hairless mice ; UVB radiation
- 刊名：Mutation Research/Genetic Toxicology and Environmental Mutagenesis
- 出版年：2016
- 出版时间：1 September 2016
- 年：2016
- 卷：807
- 期：Complete
- 页码：15-24
- 全文大小：2140 K
文摘
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Co-exposure of UVB and ZnO-NPs translocates ZnO-NPs into the nuclei of PMKs.
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Co-exposure of UVB and ZnO-NPs induces greater oxidative DNA damage in PMKs.
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Co-exposure of UVB and ZnO-NPs causes much more pronounced cell death in PMKs.
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Exposure of SKH-1 mouse skin to UVB and ZnO-NPs enhances DNA damage and cell death.