刊名:Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
出版年:2003
出版时间:September, 2003
年:2003
卷:59
期:11
页码:2611-2617
全文大小:370 K
文摘
Photobleaching of fluorophores frequently limits their detectability or observation time. We examined Indocyanine green (ICG) which is widely used in medical testing and is highly unstable. We showed that spatial localization of ICG near metallic gold colloids resulted in increased photostability. This suggests the use of fluorophore–metal conjugates in situations adversely affected by photobleaching.