Developmental expression of STATs, nuclear factor-κB and inflammatory genes in the jejunum of piglets during weaning
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- 作者：Hongbo Yi ; Denghu Jiang ; Lin Zhang ; Haitao Xiong ; Feifei Han ; Yizhen Wang ; yzwang321@zju.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：STAT ; signal transducer and activator of transcription ; CRF ; corticotrophin-releasing factor ; MAPK ; mitogen-activated protein kinase ; NF-κB ; nuclear factor-κB ; H&E ; hematoxylin and eosin ; MPO ; myeloperoxidase ; TNF ; tumor necrosis factor ; COX ; cyclooxygenase ; IFN ; interferon ; iNOS ; inducible nitric oxide synthase ; SOCS ; suppressor of cytokine signaling ; TGF ; transforming growth factor ; ETEC ; enterotoxigenic Escherichia coli ; EHEC ; enterohemorrhagic Escherichia coli
- 刊名：International Immunopharmacology
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：36
- 期：Complete
- 页码：199-204
- 全文大小：705 K
文摘
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The AKT-NF-κB pathway was activated during weaning.
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Weaning increased the phosphorylation of STAT-3.
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Weaning inhibited the phosphorylation of STAT-1 and STAT-6.
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STAT inhibitors increased bacterial infection in porcine jejunal epithelial cells.