Two new 9,19-cycloartenol glycosides from the roots of Cimicifuga simplex Wormsk
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- 作者：Yang Su ; Chuanxin Sun ; Lun Wu ; Qiuhong Wang ; Bingyou Yang ; Haixue Kuang ; 4865238@qq.com" class="auth_mail
- 关键词：1H&ndash ; 1H COSY ; 1H&ndash ; 1H correlation spectroscopy ; HSQC ; heteronuclear multiple quantum coherence ; HMBC ; heteronuclear multiple bond connectivity ; MTT ; 3-(4 ; 5-dimethylthylthiazol-2-yl)-2 ; 5-diphenyl-tetrazolium bromide ; CsA ; cyclosporine ; ConA ; concanavalin A
- 刊名：Phytochemistry Letters
- 出版年：May 2014
- 年：2014
- 卷：8
- 期：Complete
- 页码：1-5
- 全文大小：461 K
文摘
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Two new cycloartenol triterpene saponins were isolated from Cimicifuga simplex Wormsk.
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Their structures were established by detailed spectroscopic analysis, including extensive 2D NMR data.
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This is the first time to report 16,17-double bond type glycosidesaponin from Cimicifuga species.
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Their immunosuppressive activities were also carried out by ConA-stimulated T splenocyte proliferation assay in vitro.