Perinatal Major Depression Biomarkers: A systematic review
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- 作者：M. Serati ; martaserati@libero.it" class="auth_mail" title="E-mail the corresponding author ; M. Redaelli ; M. Buoli ; A.C. Altamura
- 关键词：PPD ; Postpartum Depression ; EPDS ; Edinburgh Postnatal Depression Scale ; CES-D ; Center for Epidemiological Studies Depression Scale ; BDI ; Beck Depression Inventory ; MADRS-S ; Montgomery&ndash ; Asberg Depression Rating Scale Self-rated version ; PHQ-9 ; Patient Health Questionnaire ; SAS ; Self-Rating Anxiety Scale ; SDS ; Self-rating Depression Scale ; RDC ; Research Diagnostic Criteria ; HAM-A ; Hamilton Anxiety Scale ; HAM-D ; Hamilton Rating Scale for Depression ; STA-Y ; State-Trait Anxiety Inventory ; PSQI
- 刊名：Journal of Affective Disorders
- 出版年：2016
- 出版时间：15 March 2016
- 年：2016
- 卷：193
- 期：Complete
- 页码：391-404
- 全文大小：607 K
文摘
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Postpartum depression (PPD), now termed perinatal depression by the DSM-5, is a common medical complication.
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The majority of available data on the pathophisiology of PPD have been conducted recently. Most of them deal with endocrinological and immunological biomarkers, while only few biochemical/genetic biomarkers have been investigated.
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Some robust associations with an increased risk of peripartum depression have been reported with HPA axis, hormonal changes, IL-6, vitamin D, fatty acid, BDNF.
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Affective disorders in pregnant women has to be detected as soon as possible and treated with focused therapies in order to reduce the impact of PPD on offsprings.