A prospective randomised comparative study of endoscopic band ligation versus injection sclerotherapy of bleeding internal haemorrhoids in patients with liver cirrhosis

详细信息    查看全文

• 作者：Atif ElSayed Awad ; Hanan Hamed Soliman ; Sabry Abdel Latif Abou Saif ; Abdel Monem Nooman Darwish ; Samah Mosaad ; Asem Ahmed Elfert
• 关键词：Injection sclerotherapy ; Band ligation ; Bleeding internal haemorrhoids
• 刊名：Arab Journal of Gastroenterology
• 出版年：2012
• 出版时间：June, 2012
• 年：2012
• 卷：13
• 期：2
• 页码：77-81
• 全文大小：514 K

文摘

Background and study aims

Bleeding internal haemorrhoids are common and used to be treated surgically with too many complications. Endoscopic therapy is trying to take the lead. Sclerotherapy and rubber band ligation are the candidates to replace surgical therapy especially in patients with liver cirrhosis. The aim of this study was to compare endoscopic injection sclerotherapy (EIS) to endoscopic rubber band ligation (EBL) regarding effectiveness and complications in the treatment of bleeding internal haemorrhoids in Egyptian patients with liver cirrhosis.

Patients and methods

One hundred and twenty adult patients with liver cirrhosis and bleeding internal haemorrhoids were randomised into two equal groups; the first treated with EBL using Saeed multiband ligator, and the second with EIS using either ethanolamine oleate 5 % or N-butyl cyanoacrylate. All groups were matched as regards age, sex, Child score and pre-procedure Doppler values. Patients were followed up clinically and with abdominal ultrasound/Doppler for 6 months. Endoscopic and endosonography/Doppler was done before and one month after the procedure. Pre and post-procedure data were recorded and analysed.

Results

Both techniques were highly effective in the control of bleeding from internal haemorrhoids with a low rebleeding [10 % in the EBL group and 13.33 % in the EIS group] and recurrence [20 % in the EBL group 20 % in the EIS group] rates. Child score had a positive correlation with rebleeding and recurrence in EIS group only.

Pain score and need for analgesia were significantly higher while patient satisfaction was significantly lower in EIS compared to EBL [p < 0.05]. No significant difference between ethanolamine and cyanoacrylate subgroups was found [p > 0.05].

Conclusions

Both EBL and EIS were effective in the treatment of bleeding internal haemorrhoids in patients with liver cirrhosis. EBL had significantly less pain and higher patient satisfaction than EIS. EBL was also safer in patients with advanced cirrhosis.