B-cell Non-Hodgkin Lymphomas with Plasmacytic Differentiation

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• 作者：Charles M. Harmon ; MD^a ; Lauren B. Smith ; MD^b ; ^{lbsmith@med.umich.edu" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Lymphoplasmacytic ; MALT ; Nodal marginal zone ; Splenic ; Plasmablastic ; Plasmacytic ; Lymphoma
• 刊名：Surgical Pathology Clinics
• 出版年：2016
• 出版时间：March 2016
• 年：2016
• 卷：9
• 期：1
• 页码：11-28
• 全文大小：4366 K

文摘

B-cell non-Hodgkin lymphomas with plasmacytic differentiation are a diverse group of entities with extremely variable morphologic features. Diagnostic challenges can arise in differentiating lymphoplasmacytic lymphoma from marginal zone lymphoma and other low-grade B-cell lymphomas. In addition, plasmablastic lymphomas can be difficult to distinguish from diffuse large B-cell lymphoma or other high-grade lymphomas. Judicious use of immunohistochemical studies and molecular testing can assist in appropriate classification.