- 作者：Suryakanth R. Gurudu ; Francisco C. Ramirez ; M. Edwyn Harrison ; Jonathan A. Leighton ; Michael D. Crowell
- 关键词：ADR ; adenoma detection rate ; PDR ; polyp detection rate ; PEG ; polyethylene glycol ; SDP ; split-dose preparation ; SSA ; sessile serrated adenoma
- 刊名：Gastrointestinal Endoscopy
- 出版年：2012
- 出版时间：September, 2012
- 年：2012
- 卷：76
- 期：3
- 页码：603-608.e1
- 全文大小：387 K
Background
Recent studies using split-dose preparations (SDPs) suggest a significant improvement in the quality of preparation and patient compliance. However, the effects of SDP on other quality indicators of colonoscopy, such as cecal intubation and adenoma detection rates, have not been previously reported, to our knowledge.Objective
The primary objective of this study was to compare polyp detection rates (PDRs) and adenoma detection rates (ADRs) before and after the implementation of an SDP as the preferred bowel preparation. The secondary objectives were to compare the quality of the preparation and colonoscopy completion rates before and after implementation of the SDP.
Design
Retrospective study.
Setting
Tertiary care medical center.
Patients
Patients undergoing colonoscopy for screening and surveillance of colon polyps and cancer.
Interventions
System-wide implementation of SDP.
Results
A total of 3560 patients in the pre-SDP group and 1615 patients in the post-SDP group were included in the study. SDP use increased significantly from 9 % to 74 % after implementation. In comparison with the pre-SDP group, both PDRs (44.1 % -49.5 % ;
Limitations
Retrospective design; not all endoscopists were the same in both periods.
Conclusions
System-wide implementation of an SDP as the primary choice for colonoscopy significantly improved both PDRs and ADRs, overall quality of the preparation, and colonoscopy completion rates.