Chronic kidney disease accelerates cognitive impairment in a mouse model of Alzheimer's disease, through angiotensin II

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• 作者：Takashi Nakagawa ; Yu Hasegawa ; Ken Uekawa ; Shokei Kim-Mitsuyama ; ^{mitsuyam@gpo.kumamoto-u.ac.jp}
• 关键词：Aging ; CKD ; Alzheimer's disease ; Angiotensin ; Blood-brain barrier
• 刊名：Experimental Gerontology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：87
• 期：part_PA
• 页码：108-112
• 全文大小：489 K
• 卷排序：87

文摘

Chronic kidney disease (CKD) accelerates cognitive impairment in AD mice. Angiotensin II is involved in CKD-induced cognitive impairment in AD mice. CKD causes blood brain barrier disruption in AD mice, through angiotensin II.