A shift in the balance of T17 and Treg cells in menstrual blood of women with unexplained recurrent spontaneous abortion
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- 作者：Samira Hosseinia ; Fazel Shokria ; fshokri@tums.ac.ir" class="auth_mail" title="E-mail the corresponding author ; Soheila Ansari Pourb ; Mahmood Jeddi-Tehranic ; Shohreh Nikood ; Mehdi Yousefie ; Amir-Hassan Zarnanid ; f ; zarnani@avicenna.ac.ir" class="auth_mail" title="E-mail the corresponding author ; zarnania@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：ART ; assisted reproductive technology ; FBS ; fetal bovine serum ; FITC ; fluorescein isothiocyanate ; mAb ; monoclonal Ab ; MB ; menstrual blood ; MBMC ; menstrual blood mononuclear cell ; NK cell ; natural killer cell ; PB ; peripheral blood ; PBMC ; peripheral blood mononuclear cell ; PIBF ; progesterone induced blocking factor ; PE ; phycoerythrin ; PR ; progesterone receptor ; RBC ; red blood cell ; URSA ; unexplained recurrent spontaneous abortion ; NKT cells ; NK cells ; NK cells ; natural killer cell ; Treg cell ; T re
- 刊名：Journal of Reproductive Immunology
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：116
- 期：Complete
- 页码：13-22
- 全文大小：2098 K
文摘
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T cell subsets in MB vs. PB of fertile, URSA and infertile women.
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Lower frequency of MB TCRγd+, T17 cells and T17:Treg ratio in MB of URSA patients.
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Lower frequency of CD16+ T cells in MB of all groups compared to their matched PB.
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Higher frequency of Tregs in MB of all groups compared to their matched PB.
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Higher T17:Treg ratio in MB vs. PB of only fertile women.