文摘
Leishmania is able to render the host macrophage inactive and persist inside its phagolysosome by employing immune modulatory mechanisms. Leishmania exosomes are pro-inflammatory to the host, exacerbating the pathology. Herein we provide the most recent insights on the role of exosomes and other virulence factors, especially the surface protease GP63, in Leishmania-host interactions.