The role of trapidil on neuronal apoptosis in neonatal rat model of hypoxic ischemic brain injury

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• 作者：Aytug Atici ; Gulcin Bozlu ; Ali Haydar Turhan ; Ayse Polat ; Ali Nayci ; Cetin Okuyaz ; Hakan Taskinlar
• 关键词：Trapidil ; Apoptosis ; Brain injury ; Hypoxia ; Ischemia
• 刊名：Early Human Development
• 出版年：2008
• 出版时间：April 2008
• 年：2008
• 卷：84
• 期：4
• 页码：243-247
• 全文大小：1051 K

文摘

Hypoxic ischemic brain injury (HIBI) is a common cause of neonatal mortality and morbidity. Trapidil is an antiplatelet agent and several studies demonstrate the beneficial effect of trapidil in various forms of tissue injury. The effects of trapidil on neuronal apoptosis in HIBI have not been reported previously.