Frequent detection of HCV RNA and HCVcoreAg in stool of patients with chronic hepatitis C
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- 作者：Benjamin Heidricha ; b ; c ; Heidrich.Benjamin@mh-hannover.de" class="auth_mail" title="E-mail the corresponding author ; Eike Steinmannd ; eike.steinmann@twincore.de" class="auth_mail" title="E-mail the corresponding author ; Iris Plumeierb ; Iris.Plumeier@helmholtz-hzi.de" class="auth_mail" title="E-mail the corresponding author ; Janina Kirschnera ; Kirschner.Janina@mh-hannover.de" class="auth_mail" title="E-mail the corresponding author ; Lisa Sollika ; Sollik.Lisa@mh-hannover.de" class="auth_mail" title="E-mail the corresponding author ; Szilvia Ziegerta ; Ziegert.Szilvia@mh-hannover.de" class="auth_mail" title="E-mail the corresponding author ; Michael Engelmannd ; Michael.engelmann@twincore.de" class="auth_mail" title="E-mail the corresponding author ; Patrick Lehmanna ; Lehmann.Patrick@mh-hannover.de" class="auth_mail" title="E-mail the corresponding author ; Michael Peter Mannsa ; c ; Manns.Michael@mh-hannover.de" class="auth_mail" title="E-mail the corresponding author ; Dietmar Helmut Pieperb ; Heidrich.Benjamin@mh-hannover.de" class="auth_mail" title="E-mail the corresponding author ; Heiner Wedemeyera ; c ; Heidrich.Benjamin@mh-hannover.de" class="auth_mail" title="E-mail the corresponding author
- 关键词：Hepatitis C ; HCV ; HCV RNA ; HCVcoreAg ; Transmission
- 刊名：Journal of Clinical Virology
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：80
- 期：Complete
- 页码：1-7
- 全文大小：530 K
文摘
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In 69% of patients with chronic HCV infection HCV RNA was detectable in stool.
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Patients with HCV RNA-positive stool had lower platelets and were more often male.
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Only 5 out of 68 (7%) samples tested positive for occult blood.
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In stool samples viral infectivity was detectable up to one hour in vitro.
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In bile samples viral infectivity was detectable up to eight hours in vitro.