NeuCode Proteomics Reveals Bap1 Regulation of Metabolism
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- 作者：Joshua M. Baughman1 ; 14 ; Christopher M. Rose10 ; 14 ; Ganesh Kolumam2 ; 14 ; Joshua D. Webster3 ; Emily M. Wilkerson10 ; Anna E. Merrill10 ; Timothy W. Rhoads13 ; Rajkumar Noubade4 ; Paula Katavolos5 ; Justin Lesch6 ; Donald S. Stapleton11 ; Mary E. Rabaglia11 ; Kathy L. Schueler11 ; Raymond Asuncion7 ; Melanie Domeyer7 ; Jose Zavala-Solorio2 ; Michael Reich8 ; Jason DeVoss6 ; Mark P. Keller11 ; Alan D. Attie11 ; Alexander S. Hebert13 ; Michael S. Westphall13 ; Joshua J. Coon10 ; 12 ; 13 ; 15 ; jcoon@chem.wisc.edu" class="auth_mail" title="E-mail the corresponding author ; Donald S. Kirkpatrick1 ; 15 ; kirkpatrick.donald@gene.com" class="auth_mail" title="E-mail the corresponding author ; Anwesha Dey9 ; 15 ; dey.anwesha@gene.com" class="auth_mail" title="E-mail the corresponding author
- 刊名：Cell Reports
- 出版年：2016
- 出版时间：12 July 2016
- 年：2016
- 卷：16
- 期：2
- 页码：583-595
- 全文大小：5055 K
文摘
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NeuCode is an accurate quantitative proteomics method of reducing in vivo labeling time
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Bap1 deletion perturbs multiple metabolic pathways in pancreas and liver
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Histones and mitochondrial membrane proteins are hyperubiquitinated in Bap1ko livers
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Liver-specific Bap1ko mice are perinatal lethal with metabolic defects