Ophthalmological manifestations of Parry-Romberg syndrome
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- 作者：Franziska Bucher ; MD<sup> ; sup><sup>franziskabucher@yahoo.de" class="auth_mail" title="E-mail the corresponding authorsup> ; Julia Fricke ; MD ; Antje Neugebauer ; MD ; Claus Cursiefen ; MD ; Ludwig M. Heindl ; MD
- 关键词：Parry-Romberg syndrome ; hemiatrophia faciei ; progressive hemifacial atrophy ; scleroderma ; linear scleroderma en coup de sabre ; morphea
- 刊名：Survey of Ophthalmology
- 出版年：2016
- 出版时间：November-December 2016
- 年：2016
- 卷：61
- 期：6
- 页码：693-701
- 全文大小：1503 K
文摘
Parry-Romberg syndrome is a rare disease characterized by slowly progressive atrophy affecting facial subcutaneous tissues, including the underlying muscles and osteocartilaginous structures. Various periocular, ocular, and neuro-ophthalmological manifestations have been described in Parry-Romberg syndrome. The most common periocular disorders include enophthalmos, eyelid, and orbit alterations. The most frequent ocular disorders include corneal and retinal changes, and the most common neuro-ophthalmological disorders involve optic nerve, ocular motor and pupillary dysfunction. Besides the characteristic facial abnormalities, systemic manifestations may occur, including neurologic, dermatologic, cardiac, endocrine, infectious, orthodontic, and maxillofacial disorders. So far, mainly brief case reports describe these ophthalmological findings. Therefore, we summarize the ocular, periocular, and neuro-ophthalmological findings in detail, describe diagnostic modalities, and outline therapeutic options.