Beneficial effects of vitamin C treatment on pregnant rats exposed to formaldehyde: Reversal of immunosuppression in the offspring
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- 作者：Beatriz Silva Ibrahima ; É ; ric Diego Barionia ; Cí ; ntia Heluanya ; Tá ; rcio Teodoro Bragab ; Carine Cristiane Drewesa ; Silvia Goes Costac ; Niels Olsen Saraiva Câ ; marab ; Sandra Helena Poliselli Farskya ; Adriana Lino-dos-Santos-Francoc ; alsantosfranco@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Oxidative stress ; Acute lung inflammation ; LPS ; Bone marrow ; NF-kappa B ; Toll-like receptor
- 刊名：Toxicology and Applied Pharmacology
- 出版年：2016
- 出版时间：1 June 2016
- 年：2016
- 卷：300
- 期：Complete
- 页码：77-81
- 全文大小：612 K
文摘
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FA exposure during pregnancy induces oxidative stress in the uterus.
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Vitamin C treatment blunted the oxidative stress in uterus induced by FA exposure.
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Oxidative stress in uterus after FA exposure impairs the immune response of offspring.
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Vitamin C in pregnant rats rescued the impaired immune response in the offspring.