A simple, rapid and novel method for determination of folic acid (FA) has been suggested.
FA quenches the fluorescence of BSA-modified gold nanoclusters.
In pH of 7.4, the fluorescence quenching was fitted to Stern–Volmer equation.
A linear range of 0.12–33.12 渭g mL−1 and detection limit of 18.3 ng mL−1 was achieved.