Hemoglobin Bart hydrops fetalis: A model for studying vascular changes in placental hypoxia
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文摘

Placenta villous vessels in hydrops fetalis were assessed by computer morphometry.

Hb Bart hydrops fetalis cases were used as a model for severe fetal hypoxia.

Vessels in Hb Bart cases show a greater number, perimeter, and branching pattern.

These changes reflect hypoxia at pre-placental, placental and post-placental levels.

Standardized morphometry allows studies on placenta vascular lesions to be compared.

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