Locoregional cancer therapy using polymer-based drug depots
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- 作者：Farshad Ramazani1 ; 2 ; Cornelis F. van Nostrum1 ; Gert Storm1 ; 3 ; Fabian Kiessling2 ; Twan Lammers2 ; 3 ; Wim E. Hennink1 ; Robbert J. Kok1 ; r.j.kok@uu.nl" class="auth_mail" title="E-mail the corresponding author
- 刊名：Drug Discovery Today
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：21
- 期：4
- 页码：640-647
- 全文大小：1007 K
文摘
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Polymer-based drug depots improved the median survival of patients with malignant gliomas.
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Porous microparticles hold promise for treatment of lung cancer by inhalation.
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Trans-arterially injected drug-eluting microparticles block tumor perfusion and release drug locally.
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Intraperitoneally injected microparticles allow local treatment of abdominal cancer.