HCV genotype 5: Epidemiology and spread of an uncommon genotype
详细信息 查看全文
- 作者：Jannick Verbeeck ; Hé ; lè ; ne Peigue-Lafeuille ; R. Stefan Ross ; Arm ; Abergel ; Frederik Nevens ; Schalk Van der Merwe ; Marc Van Ranst ; Cé ; cile Henquell
- 关键词：Hepatitis C virus ; HCV ; Genotype 5 ; Epidemiology ; Treatment response ; Phylogenetic analysis
- 刊名：Journal of Clinical Virology
- 出版年：2008
- 出版时间：February 2008
- 年：2008
- 卷：41
- 期：2
- 页码：170-171
- 全文大小：94 K
文摘
We report a 28-year-old immunocompetent man that after a course of corticoids developed a severe pneumonia in right lower lobe. A fiber-optic bronchoscopy showed a white membrane easily bloody on contact with bronchoscopy tube at trachea level. The tracheal biopsy showed typical cytopathological lesions of herpes simplex virus (HSV) and polymerase chain reaction was positive for type 1 HSV. Streptococcus viridans and Fusobacterium necrophorum grew in right bronchial secretion cultures. Clinical improvement was achieved after prolonged antibiotic therapy and before initiating treatment with acyclovir. Herpetic tracheitis could have been involved in the aspiration of oropharyngeal material that leaded to the development of this bacterial pneumonia.