Antibodies are not required to a protective immune response against dengue virus elicited in a mouse encephalitis model
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- 作者：Jaime Henrique Amorima ; jhamorim@usp.br" class="auth_mail" title="E-mail the corresponding author ; Rú ; bens Prince dos Santos Alvesa ; Raí ; za Bizerraa ; Sara Araú ; jo Pereiraa ; Lennon Ramos Pereiraa ; Denicar Lina Nascimento Fabrisa ; Robert Andreata Santosa ; Camila Malta Romanob ; Luí ; s Carlos de Souza Ferreiraa ; lcsf@usp.br" class="auth_mail" title="E-mail the corresponding author
- 关键词：Dengue ; Nonstructural proteins ; Immune response ; T lymphocytes ; Antibodies
- 刊名：Virology
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：487
- 期：Complete
- 页码：41-49
- 全文大小：1495 K
文摘
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Priming with a non-virulent virus.
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A protective immune response is elicited after priming with a non-virulent virus.
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Humoral immune response does not contribute to protection.
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The cellular immune response is crucial for protection.