Adolescent booster with hepatitis B virus vaccines decreases HBV infection in high-risk adults

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• 作者：Yuting Wang^a ; ¹ ; Taoyang Chen^b ; ¹ ; Ling-ling Lu^b ; Minjie Wang^c ; Dongmei Wang^a ; ^d ; Hongyu Yao^b ; Chunsun Fan^b ; Jun Qi^c ; Yawei Zhang^b ; ^e ; Chunfeng Qu^a ; ^d ; ^{quchf@cicams.ac.cn}
• 关键词：Hepatitis B virus ; Vaccination ; Adolescent booster ; Adulthood ; Maternal HBsAg status
• 刊名：Vaccine
• 出版年：2017
• 出版时间：15 February 2017
• 年：2017
• 卷：35
• 期：7
• 页码：1064-1070
• 全文大小：531 K
• 卷排序：35

文摘

Some vaccination-protected children developed chronic HBV infection in adulthood. Vaccination-protected children have increased risk when born to HBsAg(+) mothers. More anti-HBc(+) vaccinated children develop HBsAg(+) when born to HBsAg(+) mothers. Vaccinated children born to HBsAg(+) mothers benefit from adolescent booster. Adolescent booster might be appropriate for anti-HBs(−) high-risk individuals.