Chicken liver and hepatoma cell lines LMH and LMH-2A express ApoO.
Induced triglyceride accumulation in liver and LMH cells increase ApoO levels.
Production of ApoO by liver and LMH-2A cells is enhanced by estrogen.
Hepatic biosynthesis of ApoO is tightly linked to diet-induced hepatosteatosis and hormones.
ApoO is an important regulator of mitochondrial function.