An integrated electrophoretic mobility control device with split design for signal improvement in liquid chromatography-electrospray ionization mass spectrometry analysis of aminoglycosides using a heptafluorobutyric acid containing mobile phase
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- 作者：Sih-Hua Hunga ; Meng-Ju Yua ; Nan-Hsuan Wanga ; Ren-Yu Hsua ; Guor-Jien Weib ; Guor-Rong Hera ; grher@ntu.edu.tw" class="auth_mail" title="E-mail the corresponding author
- 关键词：Electrophoretic mobility control ; Ion pairing agent ; Heptafluorobutyric acid ; Aminoglycoside
- 刊名：Analytica Chimica Acta
- 出版年：2016
- 出版时间：24 August 2016
- 年：2016
- 卷：933
- 期：Complete
- 页码：156-163
- 全文大小：1654 K
文摘
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Electrophoretic mobility control was used to alleviate ion suppression due to ion pairing agent.
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An integrated electrophoretic mobility control device with a split design was fabricated.
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The proposed device could be applied to LC-ESI-MS using a conventional HPLC column.
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The device was applied to the analysis of aminoglycosides using the ion pairing agent, HFBA.