Brain activation changes during locomotion in middle-aged to older adults with multiple sclerosis
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- 作者：Manuel E. Hernandez ; Ph.D.a ; mhernand@illinois.edu" class="auth_mail" title="E-mail the corresponding author ; Roee Holtzer ; Ph.D.b ; c ; Gioella Chaparro ; M.S.a ; Kharine Jean ; B.S.d ; Julia M. Balto ; M.S.a ; Brian M. Sandroff ; Ph.D.a ; Meltem Izzetoglu ; Ph.D.e ; Robert W. Motl ; Ph.D.f
- 关键词：Multiple sclerosis ; Functional near-infrared spectroscopy ; Motor-cognitive interference ; Mobility
- 刊名：Journal of the Neurological Sciences
- 出版年：2016
- 出版时间：15 November 2016
- 年：2016
- 卷：370
- 期：Complete
- 页码：277-283
- 全文大小：494 K
文摘
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fNIRS was used to evaluate PFC oxygenation differences due to MS while walking.
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HbO2 levels were increased in persons with MS compared to controls while walking.
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MS group had greater elevations in HbO2 levels during attention-demanding walking.
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Persons with MS may be compensating for decreased efficiency by ramping up PFC activity.