vIRF3 encoded by Kaposi's sarcoma-associated herpesvirus inhibits T-cell factor-dependent transcription via a CREB-binding protein-interaction motif
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- 作者：Seho Chaa ; Joonho Choeb ; Taegun Seoa ; tseo@dongguk.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：KSHV ; vIRF3 ; TCF-dependent transcription ; Wnt signaling pathway
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：2016
- 出版时间：28 October 2016
- 年：2016
- 卷：479
- 期：4
- 页码：697-702
- 全文大小：917 K
文摘
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vIRF3 inhibits the Wnt signaling pathway.
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vIRF2 does not affect cellular localization of β-catenin.
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The LXXLL motif of vIRF3 is important for inhibition of TCF-dependent transcription.