Recent advances in the synthetic and mechanistic aspects of the ruthenium-catalyzed carbon–heteroatom bond forming reactions of alkenes and alkynes

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• 作者：Chae S. Yi ; ^a ; ^{chae.yi@marquette.edu}
• 关键词：Ruthenium catalyst ; Alkene ; Alkyne ; Carbon– ; heteroatom bond
• 刊名：Journal of Organometallic Chemistry
• 出版年：2011
• 出版时间：1 January 2011
• 年：2011
• 卷：696
• 期：1
• 页码：76-80
• 全文大小：654 K

文摘

The group’s recent advances in catalytic carbon-to-heteroatom bond forming reactions of alkenes and alkynes are described. For the C–O bond formation reaction, a well-defined bifunctional ruthenium-amido catalyst has been successfully employed for the conjugate addition of alcohols to acrylic compounds. The ruthenium-hydride complex (PCy₃)₂(CO)RuHCl was found to be a highly effective catalyst for the regioselective alkyne-to-carboxylic acid coupling reaction in yielding synthetically useful enol ester products. Cationic ruthenium-hydride catalyst generated in-situ from (PCy₃)₂(CO)RuHCl/HBF₄·OEt₂ was successfully utilized for both the hydroamination and related C–N bond forming reactions of alkenes. For the C–Si bond formation reaction, regio- and stereoselective dehydrosilylation of alkenes and hydrosilylation of alkynes have been developed by using a well-defined ruthenium-hydride catalyst. Scope and mechanistic aspects of these carbon-to-heteroatom bond forming reactions are discussed.