Epimerisation of menthol stereoisomers: Kinetic studies of the heterogeneously catalysed menthol production

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• 作者：B. Etzold ; A. Jess ; M. Nobis
• 关键词：Menthol ; Menthone ; Epimerisation ; Synthetic menthol
• 刊名：Catalysis Today
• 出版年：2009
• 出版时间：15 February 2009
• 年：2009
• 卷：140
• 期：1-2
• 页码：30-36
• 全文大小：278 K

文摘

The heterogeneously catalysed epimerisation of neomenthol and isomenthol is a key step in the synthesis of menthol in the Symrise process (formerly know as Haarmann & Reimer process). A reaction model based on the experimentally determined kinetic and thermodynamic parameters was derived for industrial relevant conditions of 150–210 °C and 0.8–7.5 MPa hydrogen pressure. Results of experiments and modelling show a good agreement and thus the derived kinetic parameters can be used for the optimisation of batch slurry processes as well as of continuous fixed bed processes.