Generative design, while keeping the centrality of human creativity, introduces a novel approach to assist humans in finding effective and esthetically convincing solutions. Meta-heuristics are a means to apply generative design in practice. We advocate the use of meta-heuristics to supporting different aspects of the UI design process. In this paper we discuss the application of genetic algorithms to solve two different problems: building hierarchical menu layouts and selecting color palettes based on a set of constraints. The paper discusses the results of two experimental applications developed in Poste Italiane, namely the money ordering by Automated Teller Machine (ATM) interfaces and the provision of financial information by kiosks.