Effect of local anesthetics on the organization and dynamics in membranes of varying phase: A fluorescence approach
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- 作者：Sandeep Shrivastava1 ; Diya Dutta1 ; Amitabha Chattopadhyay ; amit@ccmb.res.in" class="auth_mail" title="E-mail the corresponding author
- 关键词：DMPC ; 1 ; 2-dimyristoyl-sn-glycero-3-phosphocholine ; DPH ; 1 ; 6-diphenyl-1 ; 3 ; 5-hexatriene ; DPPC ; 1 ; 2-dipalmitoyl-sn-glycero-3-phosphocholine ; LUV ; large unilamellar vesicle ; PEtOH ; phenylethanol ; POPC ; 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine ; TMA-DPH ; 1-[4-(trimethylammonio)phenyl]-6-phenyl-1 ; 3 ; 5-hexatriene
- 刊名：Chemistry and Physics of Lipids
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：198
- 期：Complete
- 页码：21-27
- 全文大小：675 K
文摘
- 5">
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5">PEtOH induces disorder in membranes of varying phases.
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The extent of membrane disorder induced by PEtOH varies in a phase-specific manner.
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5">Higher PEtOH concentrations induce phase change in gel phase membranes.
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These results assume significance in the context of role of anesthetic in membrane function.