Tuning enantioselectivity in asymmetric hydrogenation of acetophenone and its derivatives via confinement effect over free-standing mesoporous palladium network catalysts
详细信息 查看全文
- 作者：Yu Wanga ; b ; Na Sua ; Lin Yea ; Yuanhang Rena ; Xueying Chena ; xueyingchen@fudan.edu.cn" class="auth_mail ; Yujue Duc ; Zhenhua Lia ; Bin Yuea ; Shik Chi Edman Tsangd ; Qiao Chene ; Heyong Hea ; heyonghe@fudan.edu.cn" class="auth_mail
- 关键词：Confinement effect ; Enantioselective hydrogenation ; Mesoporous palladium ; Acetophenone ; Aromatic ketone ; Proline ; Molecular modeling
- 刊名：Journal of Catalysis
- 出版年：May 2014
- 年：2014
- 卷：313
- 期：Complete
- 页码：113-126
- 全文大小：4106 K
文摘
- •
Free-standing mesoporous Pd was used in asymmetric hydrogenation of aromatic ketone.
- •
Enantioselectivity (ee) was effectively tuned by altering the confinement effect.
- •
Confinement effect was optimized by good control of nanoporosity and lattice property.
- •
Optimized Pd catalyst exhibited 40–73% ee at 273 K under atmospheric pressure of H2.
- •
DFT study found ee was linearly correlated with 螖E between prochiral-R & -S complexes.