Clinical effects of liraglutide are possibly influenced by hypertriglyceridemia and remaining pancreatic β-cell function in subjects with type 2 diabetes mellitus

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• 作者：Akihito Tanabe ; Hideaki Kaneto ; Shinji Kamei ; ^{s.kamei@med.kawasaki-m.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Hidenori Hirukawa ; Masashi Shimoda ; Tomohiko Kimura ; Atsushi Obata ; Seizo Okauchi ; Fuminori Tatsumi ; Kenji Kohara ; Tomoatsu Mune ; Kohei Kaku
• 关键词：Liraglutide ; Llipid control ; Pancreatic β-cell function
• 刊名：Journal of Diabetes and its Complications
• 出版年：2016
• 出版时间：August 2016
• 年：2016
• 卷：30
• 期：6
• 页码：1201-1203
• 全文大小：169 K

文摘

We searched for factors influencing the clinical effects of GLP-1 analogue liraglutide in subjects with type 2 diabetes. Multivariate analyses showed that hypertriglyceridemia and baseline HbA1c levels were independent predictors for the efficacy of liraglutide and that CPR index was an independent predictor for the durability of liraglutide.