Fecal dysbiosis in miniature dachshunds with inflammatory colorectal polyps
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- 作者：Hirotaka Igarashia ; Koichi Ohnoa ; aohno@mail.ecc.u-tokyo.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Ayako Horigomeb ; Aki Fujiwara-Igarashia ; Hideyuki Kanemotoa ; Kenjiro Fukushimaa ; Toshitaka Odamakib ; Hajime Tsujimotoa
- 关键词：Inflammatory colorectal polyp ; Inflammatory bowel disease ; Miniature dachshund ; Fecal microbiota ; 16S rRNA sequencing ; Next generation sequencer
- 刊名：Research in Veterinary Science
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：105
- 期：Complete
- 页码：41-46
- 全文大小：475 K
文摘
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Inflammatory colorectal polyp (ICRP) is commonly observed in miniature dachshund in Japan.
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Fecal microbiota was characterized by high-throughput 16S rRNA gene sequencing.
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ICRP-affected dogs showed significant fecal dysbiosis compared with healthy dogs.
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Microbiota of ICRP-affected dogs tended to change in composition to be similar to healthy after immunosuppressive therapy.