Hypoxia-inducible factor-1伪 gene polymorphisms in early and late onset preeclampsia in Sinhalese women
详细信息 查看全文
- 作者：P.H. Andraweeraa ; b ; prabha.andraweera@adelaide.edu.au" class="auth_mail ; G.A. Dekkera ; c ; S.D. Thompsona ; V.H.W. Dissanayakeb ; R.W. Jayasekarab ; C.T. Robertsa
- 关键词：Hypoxia inducible factor 1伪 ; Polymorphism ; Preeclampsia
- 刊名：Placenta
- 出版年：July 2014
- 年：2014
- 卷：35
- 期：7
- 页码：491-495
- 全文大小：216 K
文摘
- •
Early and late onset preeclampsia are now recognized as two distinct disorders.
- •
HIF1-伪 regulates many vital molecular pathways during early placentation.
- •
HIF1伪 rs11549465 was investigated in women with early and late onset preeclampsia.
- •
The T allele is protective in normal pregnancies and in late onset preeclampsia.