Spain has one of the highest proportions of dementia in the world. The RR of DDE admissions was 1.15 (1.11–1.20) for an increase of 1 dB in Leqd. The RR of DDE admissions was 1.19 (1.09–1.30) for an increase of 1 °C above 34 °C in Tmax. The RR of DDE admissions was 1.09 (1.04–1.15) for an increase of 10 μg/m3 in O3a concentrations. Diurnal traffic noise, heat waves and tropospheric ozone can exacerbate the symptoms of dementia.