Impact of Retrograde Arch Extension in Acute Type B Aortic Dissection on Management and Outcomes

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• 作者：Foeke J.H. Nauta ; MD^a ; ^b ; ^{foekenauta@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Jip L. Tolenaar ; MD ; PhD^c ; Himanshu J. Patel ; MD^b ; Jehangir J. Appoo ; MDCM^d ; Thomas T. Tsai ; MD^b ; Nimesh D. Desai ; MD ; PhD^e ; Daniel G. Montgomery ; BS^b ; Firas F. Mussa ; MD^f ; Gilbert R. Upchurch ; MD^g ; Rosella Fattori ; MD^h ; G. Chad Hughes ; MDⁱ ; Christoph A. Nienaber ; MD ; PhD^j ; Eric M. Isselbacher ; MD^k ; Kim A. Eagle ; MD^b ; Santi Trimarchi ; MD ; PhD^a ; on behalf of all International Registry of Acute Aortic Dissection (IRAD) Investigators
• 刊名：The Annals of Thoracic Surgery
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：102
• 期：6
• 页码：2036-2043
• 全文大小：640 K

文摘

Optimal management of acute type B aortic dissection with retrograde arch extension is controversial. The effect of retrograde arch extension on operative and long-term mortality has not been studied and is not incorporated into clinical treatment pathways.

Methods

The International Registry of Acute Aortic Dissection was queried for all patients presenting with acute type B dissection and an identifiable primary intimal tear. Outcomes were stratified according to management for patients with and without retrograde arch extension. Kaplan-Meier survival curves were constructed.

Results

Between 1996 and 2014, 404 patients (mean age, 63.3 ± 13.9 years) were identified. Retrograde arch extension existed in 67 patients (16.5%). No difference in complicated presentation was noted (36.8% vs 31.7%, p = 0.46), as defined by limb or organ malperfusion, coma, rupture, and shock. Patients with or without retrograde arch extension received similar treatment, with medical management in 53.7% vs 56.5% (p = 0.68), endovascular treatment in 32.8% vs 31.1% (p = 0.78), open operation in 11.9% vs 9.5% (p = 0.54), or hybrid approach in 1.5% vs 3.0% (p = 0.70), respectively. The in-hospital mortality rate was similar for patients with (10.7%) and without (10.4%) retrograde arch extension (p = 0.96), and 5-year survival was also similar at 78.3% and 77.8%, respectively (p = 0.27).

Conclusions

The incidence of retrograde arch dissection involves approximately 16% of patients with acute type B dissection. In the International Registry of Acute Aortic Dissection, this entity seems not to affect management strategy or early and late death.