A postmeningitic cochlear implant patient who was postoperatively diagnosed as having X-linked agammaglobulinemia

详细信息    查看全文

• 作者：Ryosei Minoda ; Haruo Takahashi ; Satoru Miyamaru ; Masako Masuda ; Toru Miwa ; Tetsuji Sanuki ; Toshinori Hirai ; Eiji Yumoto
• 关键词：X-linked agammaglobulinemia ; Primary immunodeficiency ; Cochlear implant
• 刊名：Auris Nasus Larynx
• 出版年：2012
• 出版时间：December, 2012
• 年：2012
• 卷：39
• 期：6
• 页码：638-640
• 全文大小：346 K

文摘

X-linked agammaglobulinemia (XLA) is caused by a mutation in the Bruton tyrosine kinase, leading to an arrest in B cell development. Consequently, patients with XLA show significant decreases in gammaglobulin. Here, we describe a child with postmeningitic deafness and XLA who underwent a cochlear implantation. His psychomotor development had been normal and his congenital immunodeficiency was noticed only postoperatively. Immunoglobulin replacement treatment was started, but he still suffered repeated infections. Eventually, his cochlear implant was removed. A preoperative check of immunological status might be advisable in postmeningitic patients undergoing cochlear implantation to reduce the risk of postoperative infectious complications.