Tissue-Specific Gene Repositioning by Muscle Nuclear Membrane Proteins Enhances Repression of Critical Developmental Genes during Myogenesis
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- 作者：Michael I. Robson1 ; Jose I. de las Heras1 ; Rafal Czapiewski1 ; Phú ; Lê ; Thà ; nh1 ; Daniel G. Booth1 ; David A. Kelly1 ; Shaun Webb1 ; Alastair R.W. Kerr1 ; Eric C. Schirmer1 ; e.schirmer@ed.ac.uk" class="auth_mail" title="E-mail the corresponding author
- 刊名：Molecular Cell
- 出版年：2016
- 出版时间：16 June 2016
- 年：2016
- 卷：62
- 期：6
- 页码：834-847
- 全文大小：5998 K
文摘
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Tissue-specific NETs direct repositioning of critical muscle genes during myogenesis
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Expression changes for NET-repositioned genes depend on cell differentiation state
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Isolating position from differentiation reveals its contribution to gene expression
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Three NETs together affect 37% of all genes normally changing in myogenesis