One-pot three-component reaction providing 1,5-benzodiazepine derivatives

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• 作者：Kenichi Murai ; Ryo Nakatani ; Yasuyuki Kita ; Hiromichi Fujioka
• 刊名：Tetrahedron
• 出版年：2008
• 出版时间：1 December 2008
• 年：2008
• 卷：64
• 期：49
• 页码：11034-11040
• 全文大小：472 K

文摘

The novel one-pot three-component reaction of aromatic aldehydes, 1,2-phenylenediamine, and β-keto esters is described. This reaction involves the γ-selective C–C bond formation of β-keto esters and produces 1,5-benzodiazepine derivatives.