- 作者：Hiroshi Tenjin ; htenjin@nn.iij4u.or.jp" class="auth_mail" title="E-mail the corresponding author ; Hiroyuki Yamamoto ; Yudai Goto ; Seisuke Tanigawa ; Hayato Takeuchi ; Yoshikazu Nakahara
- 关键词：Clipping ; Coil embolization ; Treatment selection ; Unruptured aneurysm
- 刊名：World Neurosurgery
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：91
- 期：Complete
- 页码：308-316
- 全文大小：10864 K
Methods
This study included 59 newly treated UAs in the past 2 years. We prospectively decided on criteria to recommend active treatment. UAs ≤10 mm and in ≤75 year-olds, located at in the internal carotid artery at the paraclinoid portion and the posterior circulation aneurysms except for a vertebral artery-inferior posterior cerebellar artery aneurysm were mainly treated by coil embolization, and those in the internal carotid artery except at the paraclinoid portion, in the anterior or middle cerebral artery, and in the vertebral artery-inferior posterior cerebellar artery were treated preferably by clipping. UAs with a height/neck ratio or a dome/neck ratio ≤1.4 were treated preferentially by clipping. Specific preoperative imaging and careful manipulation were adopted for clipping.
Results
Fifty-seven (96.6%) achieved modified Rankin scale (mRS) 0–1, 2 (3.4%) mRS 2–5, and 0 had mRS 6. Fifty-three UAs (89.8%) achieved complete occlusion (CO) and 7 (10.1%) had neck remnants (NR). Forty-one UAs (100%) within the criteria achieved mRS 0–1, 40 (98%) achieved CO, and 1 (2%) NR. The odds ratio of NR for those outside the criteria was 18.5 (95% confidence interval, 1.83–186.6) (P < 0.05). CO treated within the criteria was 39 and NR was 1. CO treated outside the criteria was 14 and NR was 5 (P < 0.05). The mRS 0–1 with age ≤75 years was 55 and the mRS 2–6 was 0. The mRS 0–1 with age ≥76 years was 2 and the mRS 2–6 was 2 (P < 0.01).
Conclusions
The treatment for UAs within the criteria, with the most recent points of concern, can lead to safe and complete results.