- 作者：Takuro Shinada ; Noritake Hata ; Shinya Yokoyama ; Nobuaki Kobayashi ; Kazunori Tomita ; Akihiro Shirakabe ; Masafumi Tsurumi ; Hirotake Okazaki ; Yoshiya Yamamoto
- 关键词：Arrhythmia ; Cardiac arrest ; Cardiopulmonary resuscitation ; Catecholamines
- 刊名：Journal of Cardiology
- 出版年：January, 2014
- 年：2014
- 卷：63
- 期：1
- 页码：46-52
- 全文大小：665 K
Aims
Cardio-pulmonary resuscitation and therapeutic hypothermia (TH) have improved the neurological outcomes of patients who have suffered sudden cardiac arrest; however, the benefits of and differences between cooling devices remain unclear. The aim of this study was to clarify the significance of the Arctic Sun庐 for surface cooling in patients treated with TH.Methods
Fifty-one patients (60.2 卤 14.2 years, 42 males and 9 females) who experienced cardiogenic cardiac arrest, including both shockable and non-shockable cardiac arrest, were enrolled in this study. Forty patients were treated with TH using the Arctic Sun 2000庐 for surface cooling, while the other 11 patients were treated with TH using conventional standard cooling blankets. The patients鈥?clinical courses during TH and the neurological outcomes were compared between the two groups.
Results
The body temperature before TH was not significantly different between the two groups; however, the minimal body temperature during TH was significantly lower in the patients cooled with conventional standard blankets than in those cooled using the Arctic Sun 2000庐. The rates of catecholamine administration, left ventricular ejection fraction, and mechanical support were not significantly different between the two groups; however, the maximum infusion dose of dobutamine was significantly lower in the patients with the Arctic Sun 2000庐 than in those treated with standard cooling blankets.
Conclusions
The use of TH with the Arctic Sun 2000庐 following cardiac arrest is safe and effective in precisely maintaining the target body temperature, and can be used to reduce the infusion dose of dobutamine to treat heart failure during TH.