Fibroblast Growth Factors and Vascular Endothelial Growth Factor Promote Cardiac Reprogramming under Defined Conditions
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- 作者：Hiroyuki Yamakawa1 ; Naoto Muraoka1 ; Kazutaka Miyamoto1 ; Taketaro Sadahiro1 ; Mari Isomi1 ; Sho Haginiwa1 ; Hidenori Kojima1 ; Tomohiko Umei1 ; Mizuha Akiyama1 ; Yuki Kuishi1 ; Junko Kurokawa2 ; Tetsushi Furukawa2 ; Keiichi Fukuda1 ; Masaki Ieda1 ; 3 ; mieda@z8.keio.jp" class="auth_mail" title="E-mail the corresponding author
- 刊名：Stem Cell Reports
- 出版年：2015
- 出版时间：8 December 2015
- 年：2015
- 卷：5
- 期：6
- 页码：1128-1142
- 全文大小：4547 K
文摘
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FGF2, FGF10, and VEGF (FFV) promote cardiac reprogramming under defined conditions
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FFV induces cardiac reprogramming factors through the p38MAPK and PI3K/AKT pathways
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FFV converts partially reprogrammed iCMs into fully reprogrammed functional iCMs
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FFV reduces genetic manipulations required for cardiac reprogramming