The innate immune response to Trypanosoma cruzi infection

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• 作者：Hisako Kayama ; Kiyoshi Takeda
• 关键词：Innate immunity ; Trypanosoma cruzi ; Toll-like receptor
• 刊名：Microbes and Infection
• 出版年：2010
• 出版时间：July 2010
• 年：2010
• 卷：12
• 期：7
• 页码：511-517
• 全文大小：240 K

文摘

Trypanosoma cruzi infection is a major public health problem in Latin America. The host innate immune system plays a pivotal role in the recognition of T. cruzi infection and the subsequent development of adaptive immunity. In this review, we focus on the TLR-dependent and -independent innate immune responses to T. cruzi.