Histamine and histamine receptors in Tourette syndrome and other neuropsychiatric conditions
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- 作者：Maximiliano Rapanellia ; Christopher Pittengera ; b ; c ; d ; Christopher.pittenger@yale.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Histamine ; Tourette syndrome ; Narcolepsy ; H3 receptor
- 刊名：Neuropharmacology
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：106
- 期：Complete
- 页码：85-90
- 全文大小：330 K
文摘
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Histamine dysregulation has recently been found in rare cases of Tourette syndrome.
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Histamine deficiency models aspects of Tourette syndrome in mice.
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Antagonists of the H3 receptor have potential across a range of conditions.
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H3R antagonists show promise in the treatment of hypersomnolence.