Bacterial Chemoreceptor Dynamics: Helical Stability in the Cytoplasmic Domain Varies with Functional Segment and Adaptational Modification
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- 作者：Nicholas L. Bartelli ; Gerald L. Hazelbauer ; hazelbauerg@missouri.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Tar ; chemoreceptor mediating taxis to aspartate and repellents ; EPR ; electron paramagnetic resonance ; TM2 ; transmembrane helix 2 ; TM2&prime ; transmembrane helix 2&prime ; HAMP ; histidine kinases ; adenylyl cyclases ; methyl-accepting chemoreceptors ; and phosphatases ; AS-2 ; amphipathic sequence 2 ; Tar-4E ; Tar with 4 glutamyl residues at the sites of adaptational modification ; Tar-4Q ; Tar with 4 glutaminyl residues at the sites of adaptational modification
- 刊名：Journal of Molecular Biology
- 出版年：2016
- 出版时间：25 September 2016
- 年：2016
- 卷：428
- 期：19
- 页码：3789-3804
- 全文大小：1966 K
文摘
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Helical dynamics in cytoplasmic domain of intact, bilayer-inserted chemoreceptors
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Receptor helical dynamics varies with functional segment and structural element
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Variable chemoreceptor dynamics correlates with the proportion of helical disorder.
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Adaptational modification alters chemoreceptor helical dynamics/percentage disordered.
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Ligand binding and adaptational modification alter different structural features.