Specificities and genomic distribution of somatic mammalian histone H1 subtypes
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- 作者：Lluí ; s Millá ; n-Ariñ ; o1 ; Andrea Izquierdo-Bouldstridge ; Albert Jordan ; albert.jordan@ibmb.csic.es" class="auth_mail" title="E-mail the corresponding author
- 关键词：Histone H1 ; Linker ; Variants ; Genomics
- 刊名：Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：1859
- 期：3
- 页码：510-519
- 全文大小：637 K
文摘
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Mammals have eleven histone H1 paralog variants of which seven are somatic.
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H1 variants abundance varies across cell types and during differentiation and cancer.
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H1 variants show redundant and specific functions like in gene expression.
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Despite a wide overlap, some variants seem to be enriched at different chromatin types.
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Specific features and distribution of H1 variants may depend on cell type or state